Endocrine Abstracts

Introduction: Patients with unilateral primary aldosteronism (PA) can be cured with adrenalectomy, and adrenal vein sampling (AVS) remains the gold-standard test. However, AVS is invasive, technically-challenging and criteria for determining lateralization differ between centres. 11C-Metomidate PET/CT (MTO) imaging offers a promising non-invasive alternative for identifying unilateral PA.Methods: All patients with confirmed primary aldosteronism who were...

Introduction: Mild hypercalcaemia can present in 10–15% of hyperthyroid patients. In contrast, its incidence in B cell lymphoma is considerably less (7–8%) but its levels are much higher. We report a patient with hypercalcemia secondary to both thyrotoxicosis and lymphoma.Case report: A 55 year-old lady presented with non specific symptoms of appetite loss and lower limb weakness. Comorbidities included hypertension, diabetes mellitus, hyperlip...

Introduction: One of the main challenges in the management of male hypogonadotropic hypogonadism (HH) is in the restoration of fertility. We describe 2 patients with HH and discuss the difficulties involved in their management.Case (1): A 23-year-old Chinese man presented with lack of secondary sexual characteristics. Examination revealed Tanner Stage 2 with descended testes measuring 6 ml bilaterally. Laboratory results: total testosterone (TT) <1 n...

IntroductionUnilateral PA can be cured with unilateral adrenalectomy. Adrenal vein sampling (AVS) is the current reference test to identify unilateral PA, but it is invasive and technically-difficult. 11C-metomidate PET-CT offers a non-invasive alternative to AVS. We compared the accuracy of AVS and PET-CT in identifying patients with unilateral surgically-curable PA.MethodsIn this prospective multi-centre cl...